CMap Candidate Details

Structure:
CMap ID: C00777
Pert ID: BRD-A31312900
Compound Name: montelukast
Targets: CYSLTR1
MoA: Leukotriene receptor antagonist
SMILES: CC(C)(O)c1ccccc1CCC(SCC1(CC(O)=O)CC1)c1cccc(C=Cc2ccc3ccc(Cl)cc3n2)c1
InchiKey: UCHDWCPVSPXUMX-XNTDXEJSSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49763 BRD-A31312900 A375 10 uM 6 h 0.0 0.0 0.0 -0.19 -0.66 0.01
49941 BRD-A31312900 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50104 BRD-A31312900 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50291 BRD-A31312900 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50457 BRD-A31312900 HT29 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.05 0.71
50713 BRD-A31312900 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50804 BRD-A31312900 PC3 10 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.64
51095 BRD-A31312900 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).