CMap Candidate Details

Structure:
CMap ID: C00778
Pert ID: BRD-A31374339
Compound Name: fludarabine
Targets: RRM1
MoA: DNA synthesis inhibitor
SMILES: Nc1nc(F)nc2n(cnc12)[C@@H]1O[C@H](CO)C(O)C1O
InchiKey: HBUBKKRHXORPQB-VKJDSPIKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33640 BRD-A31374339 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
33744 BRD-A31374339 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
33983 BRD-A31374339 ASC 10 uM 24 h -0.21 -0.88 0.03 0.23 0.8 0.08
34264 BRD-A31374339 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34497 BRD-A31374339 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34769 BRD-A31374339 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35043 BRD-A31374339 HT29 10 uM 6 h -0.17 -0.71 0.0 0.0 0.0 0.0
35269 BRD-A31374339 MCF??7.00 10 uM 24 h -0.28 -1.18 0.51 0.3 1.06 0.61
35508 BRD-A31374339 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35677 BRD-A31374339 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35906 BRD-A31374339 PC3 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.14
36141 BRD-A31374339 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36435 BRD-A31374339 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36731 BRD-A31374339 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.14
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).