CMap Candidate Details

Structure:
CMap ID: C00780
Pert ID: BRD-A31521121
Compound Name: methocarbamol
Targets: CA1
MoA: Muscle relaxant
SMILES: COc1ccccc1OCC(O)COC(N)=O
InchiKey: GNXFOGHNGIVQEH-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3098 BRD-A31521121 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3677 BRD-A31521121 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44760 BRD-A31521121 ASC 10 uM 24 h -0.23 -0.95 0.09 -0.29 -0.99 0.51
45081 BRD-A31521121 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45880 BRD-A31521121 NPC 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.06 0.72
46193 BRD-A31521121 PHH 10 uM 24 h -0.25 -1.06 0.24 0.0 0.0 0.0
46509 BRD-A31521121 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120512 BRD-A31521121 A375 10 uM 24 h -0.29 -1.2 0.55 0.0 0.0 0.0
120545 BRD-A31521121 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120646 BRD-A31521121 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120696 BRD-A31521121 JURKAT 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120748 BRD-A31521121 MCF??7.00 1.11 uM 24 h 0.26 1.07 0.2 -0.33 -1.11 0.89
120802 BRD-A31521121 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129001 BRD-A31521121 HA1E 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129028 BRD-A31521121 HELA 2.22 uM 3 h 0.0 0.0 0.0 0.35 1.24 1.27
129076 BRD-A31521121 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).