CMap Candidate Details

Structure:
CMap ID: C00781
Pert ID: BRD-A31575449
Compound Name: CGP-20712
Targets: ADRB1
MoA: Adrenergic receptor antagonist
SMILES: Cn1cc(nc1c2ccc(OCC(O)CNCCOc3ccc(O)c(c3)C(=O)N)cc2)C(F)(F)F
InchiKey: GKJZEKSHCJELPL-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4163 BRD-A31575449 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4517 BRD-A31575449 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4614 BRD-A31575449 PC3 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.86 0.21
37060 BRD-A31575449 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37226 BRD-A31575449 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37477 BRD-A31575449 ASC 10 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.42
37805 BRD-A31575449 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37998 BRD-A31575449 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38143 BRD-A31575449 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.32 1.14 0.87
38327 BRD-A31575449 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38843 BRD-A31575449 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).