CMap Candidate Details

Structure:
CMap ID: C07834
Pert ID: BRD-K17210248
Compound Name: daunorubicin
Targets: TOP2A
MoA: RNA synthesis inhibitor; Topoisomerase inhibitor
SMILES: COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](C[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(O)=O
InchiKey: KNAGGICVJBKDDK-XUZKBGJLSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
29801 BRD-K17210248 A375 10 uM 6 h 0.0 0.0 0.0 0.37 1.3 1.58
30172 BRD-K17210248 A549 10 uM 6 h -0.22 -0.9 0.04 0.0 0.0 0.0
30383 BRD-K17210248 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
30702 BRD-K17210248 HA1E 10 uM 6 h 0.0 0.0 0.0 0.24 0.85 0.14
30985 BRD-K17210248 HCC515 10 uM 6 h 0.0 0.0 0.0 0.37 1.31 1.59
31290 BRD-K17210248 HEPG2 10 uM 6 h -0.29 -1.2 0.55 0.21 0.76 0.05
31504 BRD-K17210248 HT29 10 uM 6 h 0.0 0.0 0.0 0.34 1.2 1.13
31843 BRD-K17210248 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32744 BRD-K17210248 PC3 10 uM 6 h 0.0 0.0 0.0 0.29 1.01 0.44
32965 BRD-K17210248 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
33439 BRD-K17210248 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).