CMap Candidate Details

Structure:
CMap ID: C00785
Pert ID: BRD-A31801025
Compound Name: formestane
Targets: CYP19A1
MoA: Aromatase inhibitor
SMILES: CC12CCC3C(CCC4C(=O)C(=O)CCC34C)C2CCC1=O
InchiKey: ZMEULISFKSVRLQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4013 BRD-A31801025 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4294 BRD-A31801025 HCC515 10 uM 24 h -0.26 -1.09 0.33 0.23 0.82 0.1
4615 BRD-A31801025 PC3 10 uM 24 h 0.0 0.0 0.0 0.34 1.19 1.01
4987 BRD-A31801025 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.2 1.17
37061 BRD-A31801025 A375 10 uM 6 h 0.0 0.0 0.0 0.31 1.09 0.67
37334 BRD-A31801025 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37478 BRD-A31801025 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37806 BRD-A31801025 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37999 BRD-A31801025 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38264 BRD-A31801025 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38328 BRD-A31801025 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38625 BRD-A31801025 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).