CMap Candidate Details

Structure:
CMap ID: C07878
Pert ID: BRD-K17378184
Compound Name: BP-897
Targets: DRD3
MoA: Dopamine receptor agonist
SMILES: COc1ccccc1N1CCN(CCCCNC(=O)c2ccc3ccccc3c2)CC1
InchiKey: MNHDKMDLOJSCGN-UHFFFAOYSA-N
Compound Aliases: PRESTWICK-559

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4072 BRD-K17378184 HA1E 10 uM 24 h -0.21 -0.86 0.02 0.0 0.0 0.0
4552 BRD-K17378184 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.84 0.18
5046 BRD-K17378184 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.84 0.17
44322 BRD-K17378184 A375 10 uM 6 h 0.22 0.92 0.04 0.0 0.0 0.0
44679 BRD-K17378184 A549 10 uM 6 h 0.0 0.0 0.0 0.25 0.87 0.17
44879 BRD-K17378184 ASC 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.4
45181 BRD-K17378184 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45449 BRD-K17378184 HT29 10 uM 6 h 0.0 0.0 0.0 0.36 1.28 1.42
45996 BRD-K17378184 NPC 10 uM 24 h -0.31 -1.29 0.77 0.0 0.0 0.0
46314 BRD-K17378184 PHH 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.35
46629 BRD-K17378184 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51596 BRD-K17378184 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51808 BRD-K17378184 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100158 BRD-K17378184 U2OS 4 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).