CMap Candidate Details

Structure:
CMap ID: C07906
Pert ID: BRD-K17497770
Compound Name: butein
Targets: ACE
MoA: Src inhibitor; EGFR inhibitor
SMILES: Oc1ccc(C(=O)C=Cc2ccc(O)c(O)c2)c(O)c1
InchiKey: AYMYWHCQALZEGT-ORCRQEGFSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4074 BRD-K17497770 HA1E 10 uM 24 h 0.25 1.03 0.13 0.0 0.0 0.0
4381 BRD-K17497770 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4656 BRD-K17497770 PC3 10 uM 24 h -0.18 -0.76 0.0 0.0 0.0 0.0
4904 BRD-K17497770 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.24
44324 BRD-K17497770 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44535 BRD-K17497770 A549 10 uM 24 h 0.0 0.0 0.0 0.29 1.04 0.55
44881 BRD-K17497770 ASC 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.15
45183 BRD-K17497770 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45451 BRD-K17497770 HT29 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.06 0.72
45661 BRD-K17497770 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45998 BRD-K17497770 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46316 BRD-K17497770 PHH 10 uM 24 h 0.22 0.91 0.03 -0.25 -0.83 0.16
46631 BRD-K17497770 SKB 10 uM 24 h 0.0 0.0 0.0 0.24 0.85 0.14
100160 BRD-K17497770 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).