CMap Candidate Details

Structure:
CMap ID: C07927
Pert ID: BRD-K17561142
Compound Name: amiodarone
Targets: KCNH2
MoA: Potassium channel blocker
SMILES: CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCN(CC)CC)c(I)c1
InchiKey: IYIKLHRQXLHMJQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9377 BRD-K17561142 AGS 10 uM 6 h 0.0 0.0 0.0 0.3 1.07 0.63
9687 BRD-K17561142 H1299 10 uM 6 h -0.23 -0.96 0.1 0.0 0.0 0.0
10262 BRD-K17561142 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.04 0.66
11436 BRD-K17561142 NCIH2073 10 uM 6 h 0.24 0.98 0.09 0.4 1.41 2.19
11727 BRD-K17561142 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12003 BRD-K17561142 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.24 0.86 0.16
12443 BRD-K17561142 PC3 10 uM 24 h -0.2 -0.84 0.01 0.0 0.0 0.0
12945 BRD-K17561142 THP1 10 uM 6 h 0.0 0.0 0.0 -0.22 -0.74 0.05
13230 BRD-K17561142 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13594 BRD-K17561142 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44680 BRD-K17561142 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44882 BRD-K17561142 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45184 BRD-K17561142 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.5 -1.69 15.65
45662 BRD-K17561142 MCF??7.00 10 uM 24 h -0.25 -1.05 0.23 0.0 0.0 0.0
46317 BRD-K17561142 PHH 10 uM 24 h 0.0 0.0 0.0 0.33 1.16 0.9
46632 BRD-K17561142 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90941 BRD-K17561142 HUH7 4 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
99008 BRD-K17561142 NEU 10 uM 6 h 0.23 0.95 0.06 -0.51 -1.71 15.65
99131 BRD-K17561142 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120251 BRD-K17561142 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120324 BRD-K17561142 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120350 BRD-K17561142 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120384 BRD-K17561142 HT29 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120487 BRD-K17561142 YAPC 0.37 uM 24 h -0.2 -0.85 0.01 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).