CMap Candidate Details

Structure:
CMap ID: C07936
Pert ID: BRD-K17588104
Compound Name: JQ-1-R
Targets: --
MoA: --
SMILES: Cc1sc-2c(c1C)C(=N[C@H](CC(=O)OC(C)(C)C)c1nnc(C)n-21)c1ccc(Cl)cc1
InchiKey: DNVXATUJJDPFDM-QGZVFWFLSA-N
Compound Aliases: JQ1-(-)

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
93640 BRD-K17588104 ASC 10 uM 24 h 0.0 0.0 0.0 0.33 1.16 0.9
93697 BRD-K17588104 CD34 10 uM 24 h 0.22 0.91 0.04 -0.27 -0.9 0.29
93823 BRD-K17588104 HEK293 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93873 BRD-K17588104 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93914 BRD-K17588104 HEPG2 1.11 uM 24 h 0.22 0.93 0.05 0.0 0.0 0.0
93952 BRD-K17588104 HUVEC 10 uM 24 h 0.32 1.34 0.89 0.0 0.0 0.0
94010 BRD-K17588104 JURKAT 0.04 uM 24 h -0.21 -0.88 0.03 0.0 0.0 0.0
94052 BRD-K17588104 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.67
94089 BRD-K17588104 NEU 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94132 BRD-K17588104 NPC 10 uM 24 h -0.28 -1.15 0.44 0.0 0.0 0.0
94187 BRD-K17588104 PC3 10 uM 24 h 0.18 0.74 0.0 -0.3 -1.02 0.61
94220 BRD-K17588104 SHSY5Y 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.15
94273 BRD-K17588104 SKL 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94323 BRD-K17588104 THP1 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.87
94367 BRD-K17588104 YAPC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118685 BRD-K17588104 A375 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118717 BRD-K17588104 A549 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118753 BRD-K17588104 HA1E 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118793 BRD-K17588104 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118877 BRD-K17588104 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).