CMap Candidate Details

Structure:
CMap ID: C00795
Pert ID: BRD-A32164164
Compound Name: methyllycaconitine
Targets: CHRNA7
MoA: Acetylcholine receptor antagonist
SMILES: CCN1CC2(COC(=O)c3ccccc3N4C(=O)CC(C)C4=O)CCC(OC)C5(C6CC7C(OC)C6C(O)(CC7OC)C8(O)C(OC)C52)C18
InchiKey: XLTANAWLDBYGFU-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1490 BRD-A32164164 HA1E 10 uM 24 h 0.0 0.0 0.0 0.27 0.95 0.31
2035 BRD-A32164164 HCC515 10 uM 6 h 0.26 1.1 0.24 0.25 0.88 0.18
2329 BRD-A32164164 PC3 10 uM 6 h -0.29 -1.23 0.63 0.2 0.72 0.02
2598 BRD-A32164164 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41659 BRD-A32164164 A375 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.86 0.21
42006 BRD-A32164164 A549 10 uM 6 h 0.0 0.0 0.0 -0.35 -1.19 1.15
42194 BRD-A32164164 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42539 BRD-A32164164 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42845 BRD-A32164164 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43257 BRD-A32164164 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43395 BRD-A32164164 NPC 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.31
43709 BRD-A32164164 PHH 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.11
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).