CMap Candidate Details

Structure:
CMap ID: C00796
Pert ID: BRD-A32172948
Compound Name: methiopril
Targets: ACE
MoA: Angiotensin converting enzyme inhibitor
SMILES: CC1CCCC(N1C(=O)CCSC(C)=O)C(O)=O
InchiKey: JHFOAISYWJRTIM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
96602 BRD-A32172948 A375 1.11 uM 24 h 0.0 0.0 0.0 -0.27 -0.89 0.27
96674 BRD-A32172948 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121988 BRD-A32172948 HELA 1.11 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.31
122017 BRD-A32172948 HT29 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.83 0.16
122064 BRD-A32172948 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122148 BRD-A32172948 MDAMB231 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122201 BRD-A32172948 THP1 3.33 uM 24 h 0.0 0.0 0.0 -0.37 -1.25 1.35
130209 BRD-A32172948 A549 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130240 BRD-A32172948 HA1E 0.03 uM 24 h -0.25 -1.05 0.23 -0.21 -0.72 0.04
130264 BRD-A32172948 HEK293 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130365 BRD-A32172948 JURKAT 0.74 uM 24 h -0.21 -0.88 0.03 0.0 0.0 0.0
130411 BRD-A32172948 MCF10A 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130437 BRD-A32172948 MCF??7.00 0.08 uM 24 h 0.0 0.0 0.0 -0.49 -1.65 15.65
130532 BRD-A32172948 YAPC 0.03 uM 24 h 0.27 1.11 0.26 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).