CMap Candidate Details

Structure:
CMap ID: C07960
Pert ID: BRD-K17674993
Compound Name: diflorasone
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: C[C@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(OC(=O)C)C(=O)COC(=O)C
InchiKey: BOBLHFUVNSFZPJ-JOYXJVLSSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4075 BRD-K17674993 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4553 BRD-K17674993 HCC515 10 uM 6 h -0.25 -1.06 0.25 0.0 0.0 0.0
4657 BRD-K17674993 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5048 BRD-K17674993 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44325 BRD-K17674993 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44536 BRD-K17674993 A549 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.3 1.61
45452 BRD-K17674993 HT29 10 uM 6 h 0.0 0.0 0.0 0.31 1.09 0.67
45784 BRD-K17674993 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45999 BRD-K17674993 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46318 BRD-K17674993 PHH 10 uM 24 h 0.23 0.98 0.09 -0.23 -0.79 0.1
100162 BRD-K17674993 U2OS 4 uM 6 h 0.19 0.8 0.0 0.3 1.05 0.58
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).