CMap Candidate Details

Structure:
CMap ID: C07972
Pert ID: BRD-K17705806
Compound Name: JTC-801
Targets: OPRL1
MoA: Opioid receptor antagonist
SMILES: CCc1ccc(OCc2ccccc2C(=O)Nc2ccc3nc(C)cc(N)c3c2)cc1
InchiKey: VTGBZWHPJFMTKS-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4659 BRD-K17705806 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5049 BRD-K17705806 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37606 BRD-K17705806 ASC 10 uM 24 h 0.0 0.0 0.0 -0.44 -1.48 15.35
95342 BRD-K17705806 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
95378 BRD-K17705806 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
95477 BRD-K17705806 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
120325 BRD-K17705806 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.33 1.15 0.89
120363 BRD-K17705806 HELA 3.33 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
120385 BRD-K17705806 HT29 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.68
120488 BRD-K17705806 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.24 0.84 0.13
128892 BRD-K17705806 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).