CMap Candidate Details

Structure:
CMap ID: C00800
Pert ID: BRD-A32269193
Compound Name: VGX-1027
Targets: TLR4
MoA: Tumor necrosis factor receptor antagonist
SMILES: OC(=O)CC1CC(=NO1)c1ccccc1
InchiKey: MUFJHYRCIHHATF-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
120519 BRD-A32269193 A375 0.125 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.48
120554 BRD-A32269193 A549 0.37 uM 24 h -0.19 -0.77 0.0 0.29 1.03 0.51
120594 BRD-A32269193 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120634 BRD-A32269193 HELA 10 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
120654 BRD-A32269193 HT29 0.04 uM 24 h -0.26 -1.1 0.34 -0.26 -0.88 0.25
120751 BRD-A32269193 MCF??7.00 1.11 uM 24 h 0.24 1.0 0.11 0.31 1.1 0.7
120813 BRD-A32269193 YAPC 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.08
129078 BRD-A32269193 PC3 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).