CMap Candidate Details

Structure:
CMap ID: C08011
Pert ID: BRD-K17823458
Compound Name: danoprevir
Targets: --
MoA: --
SMILES: CC(C)(C)OC(=O)N[C@H]1CCCCCC=C/[C@@H]2C[C@@]2(CNS(=O)(=O)C2CC2)NC(=O)[C@@H]2C[C@H](CN2C1=O)OC(=O)N1Cc2cccc(F)c2C1
InchiKey: NLLUOMDMSMVXKN-UIOHFMAFSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33785 BRD-K17823458 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34057 BRD-K17823458 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34325 BRD-K17823458 HA1E 10 uM 6 h -0.28 -1.17 0.49 0.0 0.0 0.0
34572 BRD-K17823458 HCC515 10 uM 6 h 0.21 0.88 0.01 0.0 0.0 0.0
34842 BRD-K17823458 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35106 BRD-K17823458 HT29 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.08 0.79
35401 BRD-K17823458 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35742 BRD-K17823458 NPC 10 uM 24 h 0.0 0.0 0.0 -0.16 -0.52 0.0
35940 BRD-K17823458 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36215 BRD-K17823458 PHH 10 uM 24 h 0.0 0.0 0.0 -0.18 -0.61 0.0
36785 BRD-K17823458 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.08 0.79
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).