CMap Candidate Details

Structure:
CMap ID: C08015
Pert ID: BRD-K17849083
Compound Name: tranilast
Targets: --
MoA: --
SMILES: COc1ccc(C=CC(=O)Nc2ccccc2C(O)=O)cc1OC
InchiKey: NZHGWWWHIYHZNX-CSKARUKUSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24752 BRD-K17849083 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25332 BRD-K17849083 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
52449 BRD-K17849083 PC3 10 uM 24 h 0.0 0.0 0.0 0.27 0.95 0.31
53009 BRD-K17849083 HEPG2 100 uM 48 h 0.0 0.0 0.0 -0.25 -0.83 0.16
53102 BRD-K17849083 MCF10A 30 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91106 BRD-K17849083 HUH7 10 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
120293 BRD-K17849083 A549 0.37 uM 24 h 0.23 0.94 0.06 0.0 0.0 0.0
120417 BRD-K17849083 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.69
120493 BRD-K17849083 YAPC 0.04 uM 24 h 0.26 1.1 0.24 0.0 0.0 0.0
128895 BRD-K17849083 A375 0.03 uM 24 h -0.27 -1.14 0.43 0.0 0.0 0.0
128929 BRD-K17849083 HELA 2.22 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
128956 BRD-K17849083 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).