CMap Candidate Details

Structure:
CMap ID: C08036
Pert ID: BRD-K17896185
Compound Name: FIT
Targets: OPRD1
MoA: Opioid receptor agonist
SMILES: CCC(=O)N(C1CCN(CCc2ccc(cc2)N=C=S)CC1)c1ccccc1
InchiKey: VDKBIFPJULZUPU-UHFFFAOYSA-N
Compound Aliases: fit

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1561 BRD-K17896185 HA1E 10 uM 24 h 0.0 0.0 0.0 0.37 1.32 1.71
1899 BRD-K17896185 HCC515 10 uM 24 h 0.0 0.0 0.0 0.37 1.32 1.71
2183 BRD-K17896185 PC3 10 uM 24 h 0.0 0.0 0.0 0.27 0.95 0.32
2479 BRD-K17896185 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41741 BRD-K17896185 A375 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.8 0.12
42074 BRD-K17896185 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42320 BRD-K17896185 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42650 BRD-K17896185 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.35 1.23 1.19
42953 BRD-K17896185 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43166 BRD-K17896185 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43511 BRD-K17896185 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43810 BRD-K17896185 PHH 10 uM 24 h 0.0 0.0 0.0 -0.19 -0.64 0.01
44087 BRD-K17896185 SKB 10 uM 24 h -0.2 -0.84 0.0 0.23 0.81 0.09
100167 BRD-K17896185 U2OS 10 uM 6 h 0.0 0.0 0.0 0.4 1.4 2.18
136423 BRD-K17896185 SHSY5Y 10 uM 24 h 0.0 0.0 0.0 0.33 1.16 0.9
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).