CMap Candidate Details

Structure:
CMap ID: C08048
Pert ID: BRD-K17953061
Compound Name: staurosporine
Targets: CDK2; GSK3B
MoA: PKC inhibitor
SMILES: CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35
InchiKey: HKSZLNNOFSGOKW-FYTWVXJKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
46876 BRD-K17953061 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
47421 BRD-K17953061 A549 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.77 0.09
47544 BRD-K17953061 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
47865 BRD-K17953061 HCC515 10 uM 6 h 0.0 0.0 0.0 0.32 1.15 0.88
48189 BRD-K17953061 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
48812 BRD-K17953061 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98795 BRD-K17953061 NPC 10 uM 6 h 0.0 0.0 0.0 0.25 0.88 0.19
99010 BRD-K17953061 NEU 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
119562 BRD-K17953061 HT29 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119625 BRD-K17953061 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).