CMap Candidate Details

Structure:
CMap ID: C08049
Pert ID: BRD-K17953908
Compound Name: LY-2886721
Targets: --
MoA: --
SMILES: NC1=N[C@]2(COC[C@@H]2CS1)c1cc(NC(=O)c2ccc(F)cn2)ccc1F
InchiKey: NIDRNVHMMDAAIK-MGNBDDOMSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
95502 BRD-K17953908 A549 1.11 uM 48 h 0.3 1.26 0.56 0.0 0.0 0.0
95694 BRD-K17953908 U2OS 1.11 uM 6 h -0.18 -0.74 0.0 0.0 0.0 0.0
120254 BRD-K17953908 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120421 BRD-K17953908 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120499 BRD-K17953908 YAPC 0.37 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.3
128914 BRD-K17953908 HA1E 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128932 BRD-K17953908 HELA 0.74 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
128960 BRD-K17953908 HT29 0.25 uM 24 h 0.25 1.04 0.16 0.29 1.03 0.51
128979 BRD-K17953908 PC3 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).