CMap Candidate Details

Structure:
CMap ID: C00810
Pert ID: BRD-A32917072
Compound Name: BRD-A32917072
Targets: RORC
MoA: ROR antagonist
SMILES: COc1cc(O)c(C(CC(=O)N2CCCC(C)C2)c3ccc4OCOc4c3)c(OC)c1
InchiKey: ISXDTMVXKAPUDE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
16403 BRD-A32917072 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
16536 BRD-A32917072 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
16862 BRD-A32917072 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.91 0.3
17188 BRD-A32917072 HEPG2 10 uM 6 h 0.18 0.75 0.0 0.3 1.07 0.61
17527 BRD-A32917072 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
17869 BRD-A32917072 MCF??7.00 10 uM 24 h 0.21 0.88 0.01 0.26 0.94 0.28
18205 BRD-A32917072 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
18662 BRD-A32917072 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).