CMap Candidate Details

Structure:
CMap ID: C00811
Pert ID: BRD-A32949107
Compound Name: MRS-1845
Targets: ORAI1
MoA: Calcium channel blocker
SMILES: COC(=O)C1=C(C)N(CC#C)C(=C(C1c2cccc(c2)n3oo3)C(=O)CCO)C
InchiKey: VNIMHBLANIQWNY-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1687 BRD-A32949107 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1819 BRD-A32949107 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2330 BRD-A32949107 PC3 10 uM 6 h -0.26 -1.06 0.26 0.0 0.0 0.0
2652 BRD-A32949107 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41660 BRD-A32949107 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41877 BRD-A32949107 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42195 BRD-A32949107 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42540 BRD-A32949107 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42846 BRD-A32949107 HT29 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.81 0.14
43120 BRD-A32949107 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43396 BRD-A32949107 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43710 BRD-A32949107 PHH 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.16 1.11
44002 BRD-A32949107 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).