CMap Candidate Details

Structure:
CMap ID: C00814
Pert ID: BRD-A33084410
Compound Name: 5'-guanidinonaltrindole
Targets: OPRK1
MoA: Opioid receptor antagonist
SMILES: NC(=N)Nc1ccc2[nH]c3C4Oc5c6c(CC7N(CC8CC8)CCC46C7(O)Cc3c2c1)ccc5O
InchiKey: VLNHDKDBGWXJEE-UHFFFAOYSA-N
Compound Aliases: 5'-GUANIDINONALTRINDOLE

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6631 BRD-A33084410 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6925 BRD-A33084410 A549 10 uM 24 h -0.27 -1.13 0.41 0.0 0.0 0.0
7216 BRD-A33084410 HA1E 10 uM 24 h -0.23 -0.95 0.09 0.0 0.0 0.0
7523 BRD-A33084410 HCC515 10 uM 6 h -0.19 -0.8 0.0 -0.35 -1.17 1.13
7940 BRD-A33084410 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8045 BRD-A33084410 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.68
8300 BRD-A33084410 PC3 10 uM 24 h 0.0 0.0 0.0 0.27 0.94 0.3
8565 BRD-A33084410 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.92
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).