CMap Candidate Details

Structure:
CMap ID: C00082
Pert ID: BRD-A03061970
Compound Name: alizapride
Targets: DRD2
MoA: Dopamine receptor antagonist
SMILES: COc1cc2[nH]nnc2cc1C(=O)NCC1CCCN1CC=C
InchiKey: KSEYRUGYKHXGFW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122839 BRD-A03061970 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122912 BRD-A03061970 HEK293 3.33 uM 24 h 0.27 1.13 0.29 -0.33 -1.1 0.87
122986 BRD-A03061970 HT29 10 uM 24 h -0.29 -1.19 0.54 0.0 0.0 0.0
123037 BRD-A03061970 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.37
123066 BRD-A03061970 MCF10A 0.37 uM 24 h 0.18 0.76 0.0 0.24 0.86 0.15
123080 BRD-A03061970 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 -0.44 -1.49 15.35
123127 BRD-A03061970 MDAMB231 0.37 uM 24 h 0.26 1.09 0.23 0.18 0.62 0.0
123199 BRD-A03061970 THP1 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123220 BRD-A03061970 YAPC 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131255 BRD-A03061970 A549 0.25 uM 24 h -0.24 -0.98 0.12 -0.25 -0.85 0.2
131289 BRD-A03061970 HA1E 2.22 uM 24 h 0.28 1.18 0.39 -0.31 -1.06 0.72
131313 BRD-A03061970 HELA 0.25 uM 24 h 0.0 0.0 0.0 -0.22 -0.72 0.04
131471 BRD-A03061970 PC3 0.03 uM 24 h 0.0 0.0 0.0 -0.23 -0.79 0.11
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).