CMap Candidate Details

Structure:
CMap ID: C08274
Pert ID: BRD-K18618618
Compound Name: cimetidine
Targets: HRH2
MoA: Histamine receptor antagonist
SMILES: CNC(=NC#N)NCCSCc1nc[nH]c1C
InchiKey: AQIXAKUUQRKLND-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1746 BRD-K18618618 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1900 BRD-K18618618 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.72 0.04
2190 BRD-K18618618 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2679 BRD-K18618618 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42075 BRD-K18618618 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42321 BRD-K18618618 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42651 BRD-K18618618 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42954 BRD-K18618618 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43167 BRD-K18618618 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43512 BRD-K18618618 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43811 BRD-K18618618 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44088 BRD-K18618618 SKB 10 uM 24 h 0.18 0.74 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).