CMap Candidate Details

Structure:
CMap ID: C00829
Pert ID: BRD-A33833419
Compound Name: TER-14687
Targets: PRKCQ
MoA: Inhibitor of translocation of PKCq in T cells
SMILES: CN(C)CC1Cc2ccccc2C1=O
InchiKey: IOXRKHWIYNWYFF-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4014 BRD-A33833419 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.37
4295 BRD-A33833419 HCC515 10 uM 24 h -0.23 -0.97 0.11 0.0 0.0 0.0
4743 BRD-A33833419 PC3 10 uM 6 h 0.0 0.0 0.0 0.24 0.84 0.12
4988 BRD-A33833419 VCAP 10 uM 6 h 0.25 1.04 0.15 0.28 1.0 0.42
39042 BRD-A33833419 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39393 BRD-A33833419 A549 10 uM 6 h 0.0 0.0 0.0 0.31 1.1 0.69
39563 BRD-A33833419 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39889 BRD-A33833419 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40174 BRD-A33833419 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40565 BRD-A33833419 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.34 1.19 1.01
40692 BRD-A33833419 NEU 10 uM 24 h 0.24 0.99 0.1 -0.38 -1.26 1.38
40988 BRD-A33833419 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41312 BRD-A33833419 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).