CMap Candidate Details

Structure:
CMap ID: C08329
Pert ID: BRD-K18779551
Compound Name: bifemelane
Targets: MAOA; MAOB
MoA: Acetylcholine release stimulant
SMILES: CNCCCCOc1ccccc1Cc1ccccc1
InchiKey: QSQQPMHPCBLLGX-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4386 BRD-K18779551 HCC515 10 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.63
25494 BRD-K18779551 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39641 BRD-K18779551 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39957 BRD-K18779551 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40765 BRD-K18779551 NEU 10 uM 24 h 0.0 0.0 0.0 0.34 1.21 1.15
41066 BRD-K18779551 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41395 BRD-K18779551 SKB 10 uM 24 h 0.0 0.0 0.0 0.35 1.26 1.29
99725 BRD-K18779551 U2OS 10 uM 6 h 0.0 0.0 0.0 0.25 0.87 0.17
120881 BRD-K18779551 A549 1.11 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.92
120927 BRD-K18779551 HEK293 3.33 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
120991 BRD-K18779551 HELA 10 uM 3 h 0.23 0.94 0.06 0.37 1.3 1.59
121025 BRD-K18779551 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121085 BRD-K18779551 YAPC 10 uM 24 h 0.0 0.0 0.0 -0.41 -1.39 2.02
129090 BRD-K18779551 A375 0.01 uM 24 h 0.0 0.0 0.0 -0.32 -1.06 0.73
129127 BRD-K18779551 HA1E 0.03 uM 24 h 0.24 0.99 0.1 0.26 0.91 0.23
129176 BRD-K18779551 HT29 2.22 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.66
129212 BRD-K18779551 PC3 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).