CMap Candidate Details

Structure:
CMap ID: C08334
Pert ID: BRD-K18799075
Compound Name: BAY-59-3074
Targets: CNR1; CNR2
MoA: Cannabinoid receptor partial agonist
SMILES: FC(F)(F)CCCS(=O)(=O)Oc1cccc(Oc2cccc(c2C#N)C(F)(F)F)c1
InchiKey: LWUSZIVDPJPVBW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4079 BRD-K18799075 HA1E 10 uM 24 h 0.0 0.0 0.0 0.23 0.82 0.1
4387 BRD-K18799075 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4663 BRD-K18799075 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5052 BRD-K18799075 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39099 BRD-K18799075 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39305 BRD-K18799075 A549 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.76 0.07
39642 BRD-K18799075 ASC 10 uM 24 h 0.23 0.96 0.08 0.0 0.0 0.0
39958 BRD-K18799075 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40238 BRD-K18799075 HT29 10 uM 6 h 0.21 0.9 0.02 -0.31 -1.06 0.72
40456 BRD-K18799075 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.71 0.03
40766 BRD-K18799075 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41067 BRD-K18799075 NPC 10 uM 24 h 0.27 1.11 0.25 0.3 1.07 0.61
41396 BRD-K18799075 SKB 10 uM 24 h 0.0 0.0 0.0 -0.18 -0.61 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).