CMap Candidate Details

Structure:
CMap ID: C08339
Pert ID: BRD-K18816859
Compound Name: L-694247
Targets: HTR1D
MoA: Serotonin receptor agonist
SMILES: CS(=O)(=O)Nc1ccc(Cc2noc(n2)-c2ccc3[nH]cc(CCN)c3c2)cc1
InchiKey: HKXMQLISPYELRD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2991 BRD-K18816859 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3340 BRD-K18816859 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3739 BRD-K18816859 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
22257 BRD-K18816859 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23826 BRD-K18816859 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44333 BRD-K18816859 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44890 BRD-K18816859 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45192 BRD-K18816859 HEPG2 10 uM 6 h -0.2 -0.82 0.0 0.0 0.0 0.0
45460 BRD-K18816859 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45668 BRD-K18816859 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46008 BRD-K18816859 NPC 10 uM 24 h 0.0 0.0 0.0 -0.42 -1.43 15.35
46325 BRD-K18816859 PHH 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.57
46641 BRD-K18816859 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).