CMap Candidate Details

Structure:
CMap ID: C08349
Pert ID: BRD-K18849474
Compound Name: dalcetrapib
Targets: CETP
MoA: Cholesterylester transfer protein inhibitor
SMILES: CCC(CC)CC1(CCCCC1)C(=O)Nc1ccccc1SC(=O)C(C)C
InchiKey: YZQLWPMZQVHJED-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9021 BRD-K18849474 A375 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9188 BRD-K18849474 A549 80 uM 6 h 0.0 0.0 0.0 -0.29 -0.99 0.5
9689 BRD-K18849474 H1299 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10041 BRD-K18849474 HA1E 80 uM 6 h -0.23 -0.98 0.12 -0.22 -0.73 0.04
10254 BRD-K18849474 HCC515 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10751 BRD-K18849474 HEPG2 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10956 BRD-K18849474 HT29 80 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11133 BRD-K18849474 MCF??7.00 80 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11438 BRD-K18849474 NCIH2073 80 uM 6 h -0.23 -0.96 0.1 0.28 1.0 0.42
11729 BRD-K18849474 NCIH508 80 uM 6 h 0.0 0.0 0.0 0.33 1.17 0.97
12280 BRD-K18849474 NOMO1 80 uM 6 h 0.0 0.0 0.0 0.43 1.52 2.28
12433 BRD-K18849474 PC3 80 uM 24 h 0.22 0.92 0.04 0.0 0.0 0.0
12750 BRD-K18849474 SW480 80 uM 6 h 0.0 0.0 0.0 -0.29 -0.97 0.46
13232 BRD-K18849474 U937 80 uM 6 h 0.0 0.0 0.0 -0.29 -0.97 0.46
13595 BRD-K18849474 VCAP 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).