CMap Candidate Details

Structure:
CMap ID: C00835
Pert ID: BRD-A34208323
Compound Name: VU-0404997-2
Targets: GRM4
MoA: Glutamate receptor modulator
SMILES: CC1(CC(=O)N(C1=O)c1ccc(NC(=O)c2ccccn2)cc1Cl)c1ccccc1
InchiKey: VVBFAZRDUJRAAU-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
18895 BRD-A34208323 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
19385 BRD-A34208323 A549 10 uM 6 h -0.31 -1.27 0.74 -0.23 -0.79 0.1
19545 BRD-A34208323 HA1E 10 uM 6 h 0.28 1.16 0.35 -0.23 -0.77 0.08
19866 BRD-A34208323 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.22 -0.73 0.05
20193 BRD-A34208323 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.43 -1.46 15.35
20528 BRD-A34208323 HT29 10 uM 6 h 0.19 0.81 0.0 0.31 1.08 0.66
20832 BRD-A34208323 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.71 0.04
21166 BRD-A34208323 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
21681 BRD-A34208323 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.93 0.34
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).