CMap Candidate Details

Structure:
CMap ID: C08366
Pert ID: BRD-K18909381
Compound Name: CGS-12066B
Targets: HTR1B
MoA: Serotonin receptor agonist
SMILES: CN1CCN(CC1)c2nc3cc(ccc3n4cccc24)C(F)(F)F
InchiKey: LXFHSCDLMBZYKY-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4080 BRD-K18909381 HA1E 10 uM 24 h 0.0 0.0 0.0 0.27 0.95 0.31
4388 BRD-K18909381 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24415 BRD-K18909381 A375 10 uM 6 h -0.27 -1.12 0.39 0.0 0.0 0.0
24877 BRD-K18909381 HT29 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.84 0.18
25007 BRD-K18909381 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25238 BRD-K18909381 PC3 10 uM 6 h 0.0 0.0 0.0 0.27 0.95 0.31
25336 BRD-K18909381 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.87
39306 BRD-K18909381 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39643 BRD-K18909381 ASC 10 uM 24 h -0.26 -1.1 0.34 0.0 0.0 0.0
39959 BRD-K18909381 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.35 1.22 1.15
40767 BRD-K18909381 NEU 10 uM 24 h 0.24 1.01 0.11 0.0 0.0 0.0
41068 BRD-K18909381 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41397 BRD-K18909381 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99727 BRD-K18909381 U2OS 10 uM 6 h 0.0 0.0 0.0 0.29 1.02 0.48
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).