CMap Candidate Details

Structure:
CMap ID: C08370
Pert ID: BRD-K18922609
Compound Name: neostigmine
Targets: ACHE
MoA: Acetylcholinesterase inhibitor
SMILES: CN(C)C(=O)Oc1cccc(c1)[N+](C)(C)C
InchiKey: ALWKGYPQUAPLQC-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
90919 BRD-K18922609 HUH7 15 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
97135 BRD-K18922609 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99728 BRD-K18922609 U2OS 6.66 uM 6 h 0.0 0.0 0.0 0.26 0.93 0.26
121493 BRD-K18922609 YAPC 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129423 BRD-K18922609 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129458 BRD-K18922609 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129480 BRD-K18922609 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.3 1.06 0.58
129507 BRD-K18922609 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129544 BRD-K18922609 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).