CMap Candidate Details
Structure:
| CMap ID: | C08406 |
| Pert ID: | BRD-K19034817 |
| Compound Name: | pacritinib |
| Targets: | FLT3; JAK2 |
| MoA: | JAK inhibitor; FLT3 inhibitor |
| SMILES: | C(CN1CCCC1)Oc1ccc2Nc3nccc(n3)-c3cccc(COCC=CCOCc1c2)c3 |
| InchiKey: | HWXVIOGONBBTBY-ONEGZZNKSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 95537 | BRD-K19034817 | A549 | 0.12 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.33 | 1.17 | 0.93 |
| 95580 | BRD-K19034817 | MCF??7.00 | 0.12 uM | 48 h | 0.0 | 0.0 | 0.0 | -0.24 | -0.8 | 0.11 |
| 95701 | BRD-K19034817 | U2OS | 0.12 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 96567 | BRD-K19034817 | PC3 | 1.11 uM | 24 h | 0.27 | 1.11 | 0.26 | -0.28 | -0.95 | 0.41 |
| 97169 | BRD-K19034817 | A375 | 3.33 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |