CMap Candidate Details

Structure:
CMap ID: C08423
Pert ID: BRD-K19059335
Compound Name: BRD-K19059335
Targets: RUNX1
MoA: Runt-related transcription factor inhibitor
SMILES: Clc1ccc2NC(=O)CN=C(c3ccc[nH]3)c2c1
InchiKey: XWNMORIHKRROGW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
16227 BRD-K19059335 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
16611 BRD-K19059335 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
17271 BRD-K19059335 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.34 -1.14 1.02
17613 BRD-K19059335 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
17931 BRD-K19059335 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
18422 BRD-K19059335 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
18568 BRD-K19059335 VCAP 10 uM 24 h 0.3 1.24 0.53 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).