CMap Candidate Details

Structure:
CMap ID: C08440
Pert ID: BRD-K19111024
Compound Name: clofibric-acid
Targets: PPARA
MoA: PPAR receptor agonist
SMILES: CC(C)(Oc1ccc(Cl)cc1)C(O)=O
InchiKey: TXCGAZHTZHNUAI-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3155 BRD-K19111024 HCC515 10 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.36
3947 BRD-K19111024 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39644 BRD-K19111024 ASC 10 uM 24 h 0.0 0.0 0.0 -0.2 -0.67 0.02
39960 BRD-K19111024 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.23 1.25
41398 BRD-K19111024 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98798 BRD-K19111024 NPC 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
99011 BRD-K19111024 NEU 10 uM 6 h 0.17 0.73 0.0 0.22 0.78 0.06
99730 BRD-K19111024 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
125995 BRD-K19111024 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126024 BRD-K19111024 HELA 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126044 BRD-K19111024 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126068 BRD-K19111024 HUVEC 0.04 uM 24 h -0.24 -0.99 0.13 0.0 0.0 0.0
126108 BRD-K19111024 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.67
126163 BRD-K19111024 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126251 BRD-K19111024 PC3 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
126281 BRD-K19111024 THP1 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133994 BRD-K19111024 A375 0.03 uM 24 h 0.0 0.0 0.0 0.23 0.83 0.11
134027 BRD-K19111024 A549 0.03 uM 24 h 0.0 0.0 0.0 0.25 0.88 0.19
134082 BRD-K19111024 HEK293 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
134218 BRD-K19111024 MCF??7.00 0.74 uM 24 h 0.0 0.0 0.0 0.35 1.25 1.28
134248 BRD-K19111024 MDAMB231 0.03 uM 24 h -0.16 -0.67 0.0 -0.33 -1.12 0.96
134302 BRD-K19111024 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).