CMap Candidate Details

Structure:
CMap ID: C00845
Pert ID: BRD-A34706053
Compound Name: CGP-12177
Targets: ADRB1; ADRB2; ADRB3
MoA: Adrenergic receptor agonist
SMILES: CC(C)(C)NCC(O)COc1cccc2[nH]c(=O)[nH]c12
InchiKey: ANAWRRAUQXSHKD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1491 BRD-A34706053 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1820 BRD-A34706053 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.85 0.19
2331 BRD-A34706053 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2564 BRD-A34706053 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41661 BRD-A34706053 A375 10 uM 6 h -0.24 -1.02 0.18 0.0 0.0 0.0
42007 BRD-A34706053 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42196 BRD-A34706053 ASC 10 uM 24 h 0.22 0.9 0.02 0.0 0.0 0.0
42541 BRD-A34706053 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.1 0.86
42847 BRD-A34706053 HT29 10 uM 6 h 0.0 0.0 0.0 0.22 0.78 0.07
43258 BRD-A34706053 MCF??7.00 10 uM 6 h -0.27 -1.15 0.43 0.0 0.0 0.0
43397 BRD-A34706053 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43711 BRD-A34706053 PHH 10 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.49
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).