CMap Candidate Details

Structure:
CMap ID: C08453
Pert ID: BRD-K19146323
Compound Name: STK-661558
Targets: --
MoA: --
SMILES: Clc1ccc2c(ccnc2c1)N1CCN(CC1)C(=O)c1ccc(Cl)c(Cl)c1
InchiKey: AOIWSYFLKMQHLZ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
19420 BRD-K19146323 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20277 BRD-K19146323 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20603 BRD-K19146323 HT29 10 uM 6 h 0.28 1.15 0.34 0.0 0.0 0.0
21038 BRD-K19146323 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
21374 BRD-K19146323 PC3 10 uM 6 h 0.24 0.98 0.09 0.33 1.18 0.99
21542 BRD-K19146323 VCAP 10 uM 24 h 0.22 0.9 0.02 0.0 0.0 0.0
25646 BRD-K19146323 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
26297 BRD-K19146323 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
26632 BRD-K19146323 HA1E 10 uM 6 h -0.21 -0.85 0.01 0.18 0.63 0.0
26943 BRD-K19146323 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.22 -0.75 0.07
27878 BRD-K19146323 NEU 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.25 1.35
28188 BRD-K19146323 NPC 10 uM 24 h -0.31 -1.3 0.81 0.32 1.12 0.74
28826 BRD-K19146323 PHH 10 uM 24 h 0.22 0.9 0.03 -0.26 -0.88 0.25
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).