CMap Candidate Details

Structure:
CMap ID: C08471
Pert ID: BRD-K19203487
Compound Name: SPP-301
Targets: --
MoA: --
SMILES: COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OC)-c1ccncc1
InchiKey: YBWLTKFZAOSWSM-UHFFFAOYSA-N
Compound Aliases: avosentan

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
90637 BRD-K19203487 HCT116 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90659 BRD-K19203487 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
97996 BRD-K19203487 HA1E 10 uM 24 h 0.23 0.95 0.07 -0.28 -0.94 0.36
98029 BRD-K19203487 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98079 BRD-K19203487 P1A82 3.33 uM 24 h -0.18 -0.76 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).