CMap Candidate Details

Structure:
CMap ID: C00849
Pert ID: BRD-A34806832
Compound Name: proscillaridin
Targets: ATP1A1
MoA: ATPase inhibitor
SMILES: C[C@@H]1O[C@@H](O[C@H]2CC[C@]3(C)C4CC[C@]5(C)[C@H](CC[C@]5(O)C4CCC3=C2)c6ccc(=O)oc6)[C@H](O)[C@H](O)[C@H]1O
InchiKey: MYEJFUXQJGHEQK-BVLCKXLMSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5262 BRD-A34806832 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.38 -1.27 1.43
5514 BRD-A34806832 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6240 BRD-A34806832 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37064 BRD-A34806832 A375 10 uM 6 h 0.0 0.0 0.0 -0.44 -1.49 15.35
37335 BRD-A34806832 A549 10 uM 6 h 0.0 0.0 0.0 -0.6 -2.01 15.65
37482 BRD-A34806832 ASC 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.21 1.24
37808 BRD-A34806832 HEPG2 10 uM 6 h -0.23 -0.96 0.1 -0.5 -1.7 15.65
38002 BRD-A34806832 HT29 10 uM 6 h 0.0 0.0 0.0 -0.5 -1.67 15.65
38147 BRD-A34806832 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.48 -1.6 15.65
38332 BRD-A34806832 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38847 BRD-A34806832 SKB 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.18 1.14
88524 BRD-A34806832 VCAP 0.37 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
96064 BRD-A34806832 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).