CMap Candidate Details
Structure:
| CMap ID: | C08496 |
| Pert ID: | BRD-K19277754 |
| Compound Name: | paroxetine |
| Targets: | SLC6A4 |
| MoA: | Selective serotonin reuptake inhibitor |
| SMILES: | CN1CC[C@H]([C@H](COc2ccc3OCOc3c2)C1)c1ccc(F)cc1 |
| InchiKey: | MOJZPKOBKCXNKG-YJBOKZPZSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 24416 | BRD-K19277754 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24561 | BRD-K19277754 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.26 | 0.94 | 0.28 |
| 24755 | BRD-K19277754 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.35 | 1.25 | 1.29 |
| 24878 | BRD-K19277754 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25088 | BRD-K19277754 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25239 | BRD-K19277754 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.44 | -1.48 | 15.35 |
| 25337 | BRD-K19277754 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |