CMap Candidate Details

Structure:
CMap ID: C08497
Pert ID: BRD-K19284129
Compound Name: salvinorin-a
Targets: OPRK1
MoA: Opioid receptor agonist
SMILES: COC(=O)[C@@H]1C[C@H](OC(C)=O)C(=O)[C@H]2[C@@]1(C)CC[C@H]1C(=O)O[C@@H](C[C@]21C)c1ccoc1
InchiKey: OBSYBRPAKCASQB-AGQYDFLVSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3156 BRD-K19284129 HCC515 10 uM 24 h 0.0 0.0 0.0 0.21 0.76 0.04
3741 BRD-K19284129 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44542 BRD-K19284129 A549 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.69 0.02
45194 BRD-K19284129 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.24 0.84 0.12
46327 BRD-K19284129 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46643 BRD-K19284129 SKB 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.02
87904 BRD-K19284129 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87961 BRD-K19284129 NPC 0.125 uM 24 h 0.0 0.0 0.0 -0.28 -0.96 0.42
120854 BRD-K19284129 A375 0.04 uM 24 h 0.0 0.0 0.0 0.23 0.83 0.11
120931 BRD-K19284129 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.62
121089 BRD-K19284129 YAPC 0.125 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.5
129128 BRD-K19284129 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129146 BRD-K19284129 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129180 BRD-K19284129 HT29 0.25 uM 24 h -0.35 -1.44 1.43 -0.28 -0.94 0.37
129213 BRD-K19284129 PC3 0.03 uM 24 h 0.25 1.03 0.14 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).