CMap Candidate Details

Structure:
CMap ID: C00085
Pert ID: BRD-A03216249
Compound Name: mepivacaine
Targets: --
MoA: --
SMILES: CN1CCCCC1C(=O)Nc1c(C)cccc1C
InchiKey: INWLQCZOYSRPNW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
22625 BRD-A03216249 HCC515 10 uM 6 h -0.18 -0.73 0.0 0.0 0.0 0.0
22906 BRD-A03216249 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.88 0.24
24071 BRD-A03216249 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122869 BRD-A03216249 HA1E 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122921 BRD-A03216249 HEK293 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122994 BRD-A03216249 HT29 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123046 BRD-A03216249 JURKAT 1.11 uM 24 h -0.29 -1.21 0.6 0.28 0.98 0.37
123083 BRD-A03216249 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123136 BRD-A03216249 MDAMB231 10 uM 24 h 0.32 1.32 0.79 0.41 1.43 2.21
123206 BRD-A03216249 THP1 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131220 BRD-A03216249 A375 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131262 BRD-A03216249 A549 0.25 uM 24 h 0.0 0.0 0.0 0.3 1.05 0.57
131318 BRD-A03216249 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131383 BRD-A03216249 HUVEC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131418 BRD-A03216249 MCF10A 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131475 BRD-A03216249 PC3 0.25 uM 24 h 0.18 0.77 0.0 0.0 0.0 0.0
131516 BRD-A03216249 YAPC 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).