CMap Candidate Details

Structure:
CMap ID: C00850
Pert ID: BRD-A34817987
Compound Name: itraconazole
Targets: --
MoA: --
SMILES: CCC(C)n1ncn(c2ccc(cc2)N3CCN(CC3)c4ccc(OCC5COC(Cn6cncn6)(O5)c7ccc(Cl)cc7Cl)cc4)c1=O
InchiKey: VHVPQPYKVGDNFY-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9284 BRD-A34817987 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9589 BRD-A34817987 H1299 10 uM 6 h -0.29 -1.21 0.59 -0.23 -0.77 0.09
9964 BRD-A34817987 HA1E 10 uM 24 h 0.23 0.97 0.08 0.0 0.0 0.0
11213 BRD-A34817987 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11651 BRD-A34817987 NCIH508 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11906 BRD-A34817987 NCIH596 10 uM 6 h 0.0 0.0 0.0 -0.39 -1.3 1.57
12203 BRD-A34817987 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12537 BRD-A34817987 PC3 10 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.63
13064 BRD-A34817987 THP1 10 uM 6 h 0.29 1.2 0.43 -0.27 -0.91 0.31
25286 BRD-A34817987 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91439 BRD-A34817987 HUH7 4 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
115947 BRD-A34817987 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
115983 BRD-A34817987 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
116065 BRD-A34817987 HCC515 10 uM 24 h 0.23 0.96 0.07 0.0 0.0 0.0
116108 BRD-A34817987 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.72
116154 BRD-A34817987 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).