CMap Candidate Details

Structure:
CMap ID: C08524
Pert ID: BRD-K19360254
Compound Name: ergocornine
Targets: DRD2
MoA: Dopamine receptor agonist
SMILES: CC(C)[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]7CCCN7C1=O)C(C)C
InchiKey: UJYGDMFEEDNVBF-OGGGUQDZSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4082 BRD-K19360254 HA1E 10 uM 24 h 0.26 1.08 0.21 -0.25 -0.85 0.19
4390 BRD-K19360254 HCC515 10 uM 24 h 0.26 1.07 0.2 0.0 0.0 0.0
4788 BRD-K19360254 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5054 BRD-K19360254 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39101 BRD-K19360254 A375 10 uM 6 h 0.18 0.73 0.0 0.0 0.0 0.0
39432 BRD-K19360254 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39646 BRD-K19360254 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39962 BRD-K19360254 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40240 BRD-K19360254 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40597 BRD-K19360254 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40769 BRD-K19360254 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41070 BRD-K19360254 NPC 10 uM 24 h -0.25 -1.05 0.23 0.0 0.0 0.0
41400 BRD-K19360254 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).