CMap Candidate Details

Structure:
CMap ID: C00856
Pert ID: BRD-A35033682
Compound Name: eriodictyol
Targets: NFE2L2
MoA: Cytochrome P450 inhibitor
SMILES: Oc1cc(O)c2C(=O)CC(Oc2c1)c3ccc(O)c(O)c3
InchiKey: SBHXYTNGIZCORC-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2802 BRD-A35033682 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3099 BRD-A35033682 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3436 BRD-A35033682 PC3 10 uM 24 h -0.28 -1.15 0.44 -0.21 -0.69 0.02
3678 BRD-A35033682 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44242 BRD-A35033682 A375 10 uM 6 h 0.0 0.0 0.0 0.4 1.42 2.2
44481 BRD-A35033682 A549 10 uM 24 h -0.21 -0.89 0.03 0.0 0.0 0.0
44761 BRD-A35033682 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45083 BRD-A35033682 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45358 BRD-A35033682 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45742 BRD-A35033682 MCF??7.00 10 uM 6 h -0.33 -1.39 1.09 -0.26 -0.89 0.27
45881 BRD-A35033682 NPC 10 uM 24 h 0.0 0.0 0.0 0.24 0.84 0.13
46196 BRD-A35033682 PHH 10 uM 24 h 0.0 0.0 0.0 0.3 1.05 0.57
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).