CMap Candidate Details

Structure:
CMap ID: C08579
Pert ID: BRD-K19525698
Compound Name: ozagrel
Targets: TBXAS1
MoA: Thromboxane synthase inhibitor
SMILES: OC(=O)C=Cc1ccc(Cn2ccnc2)cc1
InchiKey: SHZKQBHERIJWAO-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1562 BRD-K19525698 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.17
2092 BRD-K19525698 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2383 BRD-K19525698 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2505 BRD-K19525698 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42076 BRD-K19525698 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42322 BRD-K19525698 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42955 BRD-K19525698 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43513 BRD-K19525698 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43812 BRD-K19525698 PHH 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
52136 BRD-K19525698 MCF??7.00 10 uM 6 h -0.23 -0.98 0.11 0.3 1.08 0.65
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).