CMap Candidate Details

Structure:
CMap ID: C00860
Pert ID: BRD-A35108200
Compound Name: dexamethasone
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO
InchiKey: UREBDLICKHMUKA-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8870 BRD-A35108200 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9285 BRD-A35108200 AGS 10 uM 6 h -0.23 -0.94 0.08 0.31 1.08 0.66
9903 BRD-A35108200 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.82
10151 BRD-A35108200 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.92
10902 BRD-A35108200 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11160 BRD-A35108200 MCF??7.00 10 uM 24 h 0.19 0.79 0.0 0.32 1.15 0.89
11907 BRD-A35108200 NCIH596 10 uM 6 h 0.0 0.0 0.0 -0.34 -1.13 0.98
12204 BRD-A35108200 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12470 BRD-A35108200 PC3 10 uM 24 h 0.0 0.0 0.0 0.32 1.15 0.88
12662 BRD-A35108200 SW480 10 uM 6 h 0.18 0.73 0.0 0.0 0.0 0.0
13531 BRD-A35108200 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.0 0.53
19212 BRD-A35108200 A549 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.66
20195 BRD-A35108200 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
90784 BRD-A35108200 HPTEC 10 uM 6 h 0.0 0.0 0.0 0.26 0.91 0.23
95799 BRD-A35108200 NPC 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
95892 BRD-A35108200 YAPC 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).