CMap Candidate Details

Structure:
CMap ID: C00867
Pert ID: BRD-A35338386
Compound Name: NECA
Targets: ADORA1; ADORA2A; ADORA2B
MoA: Adenosine receptor agonist
SMILES: CCNC(=O)C1OC(C(O)C1O)n2cnc3c(N)ncnc23
InchiKey: JADDQZYHOWSFJD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4165 BRD-A35338386 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.2 1.18
4519 BRD-A35338386 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.07 0.75
4746 BRD-A35338386 PC3 10 uM 6 h 0.21 0.86 0.01 -0.32 -1.07 0.78
4991 BRD-A35338386 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.99 0.5
37065 BRD-A35338386 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37229 BRD-A35338386 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37483 BRD-A35338386 ASC 10 uM 24 h -0.19 -0.78 0.0 -0.3 -1.0 0.52
37809 BRD-A35338386 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38257 BRD-A35338386 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38333 BRD-A35338386 NPC 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.4
38848 BRD-A35338386 SKB 10 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.48
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).