CMap Candidate Details

Structure:
CMap ID: C08702
Pert ID: BRD-K19894101
Compound Name: MST-312
Targets: TERT
MoA: Telomerase inhibitor
SMILES: Oc1cccc(C(=O)Nc2cccc(NC(=O)c3cccc(O)c3O)c2)c1O
InchiKey: MIQUEZGHEJGPJB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9092 BRD-K19894101 A549 12 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.47
9382 BRD-K19894101 AGS 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9693 BRD-K19894101 H1299 12 uM 6 h -0.3 -1.24 0.67 0.0 0.0 0.0
10044 BRD-K19894101 HA1E 12 uM 6 h -0.23 -0.98 0.11 0.0 0.0 0.0
10479 BRD-K19894101 HCT116 12 uM 6 h 0.0 0.0 0.0 -0.35 -1.17 1.12
10754 BRD-K19894101 HEPG2 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10959 BRD-K19894101 HT29 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11273 BRD-K19894101 MCF??7.00 12 uM 6 h -0.24 -0.99 0.14 -0.29 -0.98 0.47
11442 BRD-K19894101 NCIH2073 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12008 BRD-K19894101 NCIH596 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12597 BRD-K19894101 PC3 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12754 BRD-K19894101 SW480 12 uM 6 h -0.23 -0.94 0.08 0.0 0.0 0.0
13459 BRD-K19894101 VCAP 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118387 BRD-K19894101 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118499 BRD-K19894101 HCC515 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).